The YOD1 Polyclonal Antibody (CAB13270) is a valuable tool for researchers studying the role of YOD1, a deubiquitinating enzyme involved in the regulation of cellular processes such as protein degradation and DNA repair. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the YOD1 protein, this antibody enables the detection and analysis of YOD1 in a variety of cell types, making it well-suited for studies in cell biology and molecular biology.YOD1, also known as OTU deubiquitinase 1, plays a crucial role in maintaining cellular homeostasis by controlling the levels of ubiquitinated proteins within cells.
Dysregulation of YOD1 expression has been linked to various diseases, including cancer and neurodegenerative disorders. Therefore, a thorough understanding of YOD1 function is essential for developing targeted therapies and treatments for these conditions.Overall, the YOD1 Polyclonal Antibody is a reliable tool for researchers seeking to gain insights into the molecular mechanisms regulated by YOD1 and its potential implications for human health.
Product Name:
YOD1 Rabbit Polyclonal Antibody
SKU:
CAB13270
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human YOD1 (NP_061036.3).
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55432
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of K-562, using YOD1 antibody (CAB13270) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
