The YME1L1 Polyclonal Antibody (CAB10402) is a valuable tool for researchers studying the YME1L1 protein, which is involved in mitochondrial protein quality control and metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the YME1L1 protein, this antibody enables the detection and analysis of YME1L1 in various cellular contexts, making it suitable for investigations in mitochondrial biology and related areas of research.YME1L1 is a critical component of the mitochondrial proteolytic system, playing a key role in maintaining mitochondrial function and cellular metabolism.
Dysregulation of YME1L1 has been associated with mitochondrial dysfunction, aging-related diseases, and metabolic disorders. Therefore, elucidating the function and regulation of YME1L1 is essential for advancing our understanding of mitochondrial biology and its implications in human health and disease. Researchers can leverage the YME1L1 Polyclonal Antibody to explore these mechanisms and pave the way for potential therapeutic interventions targeting mitochondrial dysfunction.
Product Name:
YME1L1 Rabbit Polyclonal Antibody
SKU:
CAB10402
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human YME1L1 (NP_055078.1).
The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10730
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using YME1L1 Rabbit pAb (CAB10402) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
