The YES1 Polyclonal Antibody (CAB0628) is a valuable tool for studies involving the YES1 protein, a member of the Src family of non-receptor tyrosine kinases. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the YES1 protein, researchers can easily detect and analyze its expression in a variety of cell types, making it an ideal choice for investigations in cell signaling pathways and cancer research.
YES1 is known for its role in promoting cell growth, proliferation, and survival, as well as its involvement in cellular transformation and tumorigenesis. Its significance in these processes makes it a compelling target for research aimed at understanding the molecular mechanisms underlying cancer development and progression. By studying the activity of YES1, researchers can gain valuable insights into potential therapeutic strategies for targeting this protein in various types of cancer.
Product Name:
YES1 Rabbit Polyclonal Antibody
SKU:
CAB0628
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human YES1 (NP_005424.1).
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.
Purification Method:
Affinity purification
Gene ID:
7525
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using YES1 antibody (CAB0628) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
