The YEATS4 Polyclonal Antibody (CAB6318) is a valuable tool for researchers studying the YEATS4 protein, a key player in chromatin remodeling and transcription regulation. This antibody, generated in rabbits, has high specificity for human samples and is validated for use in Western blot and immunohistochemistry applications.YEATS4, also known as YEATS Domain Containing 4, is involved in the recognition of histone acetylation marks and plays a crucial role in gene transcription and DNA repair processes. Dysregulation of YEATS4 has been linked to various diseases, including cancer and neurological disorders, making it a promising target for therapeutic interventions.
By using this antibody, researchers can detect and analyze the expression and localization of YEATS4 in different cell types, providing insights into its function and potential implications in disease mechanisms. The YEATS4 Polyclonal Antibody is a valuable tool for studies in epigenetics, cancer biology, and other research areas where chromatin dynamics and gene expression are of interest.
Product Name:
YEATS4 Rabbit Polyclonal Antibody
SKU:
CAB6318
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human YEATS4 (NP_006521.1).
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
8089
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using YEATS4 Rabbit pAb (CAB6318) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
