The YAP1 Rabbit Polyclonal Antibody (CAB17075) is a valuable tool for researchers studying the YAP1 protein, a key regulator of cell growth, proliferation, and organ size. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in Western blot and immunohistochemistry applications.YAP1, a transcriptional co-activator, is a crucial component of the Hippo signaling pathway and plays a central role in controlling cell fate and tissue homeostasis. Dysregulation of YAP1 has been implicated in various cancers, making it an attractive target for cancer research and therapy development.By targeting the YAP1 protein, researchers can gain insight into the mechanisms underlying tumorigenesis, metastasis, and drug resistance.
The YAP1 Rabbit Polyclonal Antibody enables precise detection and analysis of YAP1 expression in a variety of cell types, providing valuable information for studies in oncology and cell biology.Overall, the YAP1 Rabbit Polyclonal Antibody is a reliable tool for investigators seeking to understand the role of YAP1 in cancer development and progression, as well as in normal tissue homeostasis. Its specificity and sensitivity make it a valuable asset for research in the fields of oncology, cell biology, and regenerative medicine.
Product Name:
YAP1 Rabbit Polyclonal Antibody
SKU:
CAB17075
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 276-488 of mouse YAP1 (NP_001164618.1).
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
10413
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using YAP1 Rabbit pAb (CAB17075) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
