null

YAP1 Rabbit Polyclonal Antibody (CAB17075)

SKU:
CAB17075
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:YAP1 Rabbit Polyclonal Antibody
SKU:CAB17075
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 276-488 of mouse YAP1 (NP_001164618.1).
Sequence:QGGV LGGG SSNQ QQQI QLQQ LQME KERL RLKQ QELF RQAI RNIN PSTA NAPK CQEL ALRS QLPT LEQD GGTP NAVS SPGM SQEL RTMT TNSS DPFL NSGT YHSR DEST DSGL SMSS YSIP RTPD DFLN SVDE MDTG DTIS QSTL PSQQ SRFP DYLE ALPG TNVD LGTL EGDA MNIE GEEL MPSL QEAL SSEI LDVE SVLA ATKL DKES FLTW L
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:YAP; YKI; COB1; YAP2; YAP-1; YAP65; YAP1
Positive Sample:A-549,DU145,NIH/3T3,HeLa,Mouse lung
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:54kDa
Observed MW:72kDa

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:10413
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using YAP1 Rabbit pAb (CAB17075) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

Related Products