YAP1 Rabbit Monoclonal Antibody (CAB19134)
- SKU:
- CAB19134
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | YAP1 Rabbit Monoclonal Antibody |
SKU: | CAB19134 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1). |
Sequence: | PTAQ HLRQ SSFE IPDD VPLP AGWE MAKT SSGQ RYFL NHID QTTT WQDP RKAM LSQM NVTA PTSP PVQQ NMMN SASG PLPD GWEQ AMTQ DGEI YYIN HKNK TTSW LDPR LDPR FAMN QRIS QSAP VKQP PPLA PQSP QGGV MGGS NSNQ QQQM RLQQ LQME KERL RLKQ QELL RQAM RNIN PSTA NSPK CQEL ALRS QLPT LEQD GGTQ NPVS SPGM SQEL RTMT TNSS DPFL NSGT YHSR DEST DSGL SMSS YSVP RTPD DFLN SVDE MDTG DTIN QSTL PSQQ NRFP DYLE AIPG TNVD LGTL EGDG MNIE GEEL MPSL QEAL SSDI LNDM ESVL AATK LDKE SFLT WL |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:2000 - 1:4000 IHC-P,1:100 - 1:500 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | YAP; YKI; COB1; YAP2; YAP-1; YAP65; P1 |
Positive Sample: | HeLa,Mouse heart,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa |
Observed MW: | 72kDa |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 10413 |
Clone Number: | ARC53477 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |