The YAP1 Polyclonal Antibody (CAB11265) is a valuable tool for researchers studying the YAP1 protein, a key player in cellular signaling pathways that regulate cell growth, proliferation, and survival. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the YAP1 protein, this antibody enables precise detection and analysis in various cell types, making it an essential resource for studies in cell biology, cancer research, and developmental biology.YAP1, also known as Yes-associated protein 1, is a transcriptional co-activator that interacts with multiple pathways to control gene expression and influence cell fate decisions.
Dysregulation of YAP1 has been implicated in various diseases, including cancer, where it promotes tumor progression and metastasis. Understanding the function of YAP1 is critical for uncovering its role in disease development and identifying potential therapeutic targets for intervention.Overall, the YAP1 Polyclonal Antibody (CAB11265) offers researchers a reliable tool for studying the biological functions of YAP1 and its implications for human health and disease. Its high specificity and sensitivity make it a valuable asset for uncovering new insights into cellular signaling pathways and advancing our understanding of YAP1's role in various physiological processes.
Product Name:
YAP1 Rabbit Polyclonal Antibody
SKU:
CAB11265
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1).
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
10413
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Hela cells, using YAP1 Rabbit pAb (CAB11265) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
