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[KO Validated] YAP1 Rabbit Polyclonal Antibody (CAB11264)

SKU:
CAB11264
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • KO Validated Antibodies 1 Anti-YAP1 Antibody CAB11264KO Validated
  • KO Validated Antibodies 1 Anti-YAP1 Antibody CAB11264KO Validated
  • KO Validated Antibodies 1 Anti-YAP1 Antibody CAB11264KO Validated
  • KO Validated Antibodies 1 Anti-YAP1 Antibody CAB11264KO Validated
  • KO Validated Antibodies 1 Anti-YAP1 Antibody CAB11264KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] YAP1 Rabbit Polyclonal Antibody
SKU:CAB11264
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1).
Sequence:PTAQ HLRQ SSFE IPDD VPLP AGWE MAKT SSGQ RYFL NHID QTTT WQDP RKAM LSQM NVTA PTSP PVQQ NMMN SASG PLPD GWEQ AMTQ DGEI YYIN HKNK TTSW LDPR LDPR FAMN QRIS QSAP VKQP PPLA PQSP QGGV MGGS NSNQ QQQM RLQQ LQME KERL RLKQ QELL RQAM RNIN PSTA NSPK CQEL ALRS QLPT LEQD GGTQ NPVS SPGM SQEL RTMT TNSS DPFL NSGT YHSR DEST DSGL SMSS YSVP RTPD DFLN SVDE MDTG DTIN QSTL PSQQ NRFP DYLE AIPG TNVD LGTL EGDG MNIE GEEL MPSL QEAL SSDI LNDM ESVL AATK LDKE SFLT WL
Tested Applications:WB IP ELISA
Recommended Dilution:WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:YAP; YKI; COB1; YAP2; YAP-1; YAP65; P1
Positive Sample:A-549,HeLa,BT-474,Mouse liver
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:54kDa
Observed MW:75kDa

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:10413
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using [KO Validated] YAP1 Rabbit pAb (CAB11264) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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