Ku70 Rabbit Polyclonal Antibody (CAB7330)
- SKU:
- CAB7330
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Ku70 Rabbit Polyclonal Antibody |
SKU: | CAB7330 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 501-600 of human Ku70 (NP_001460.1). |
Sequence: | EQAV DLTL PKVE AMNK RLGS LVDE FKEL VYPP DYNP EGKV TKRK HDNE GSGS KRPK VEYS EEEL KTHI SKGT LGKF TVPM LKEA CRAY GLKS GLKK QELL |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | ML8; KU70; TLAA; CTC75; CTCBF; G22P1; Ku70 |
Positive Sample: | COS-7,SW480,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 70kDa |
Observed MW: | 70kDa |
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Purification Method: | Affinity purification |
Gene ID: | 2547 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |