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XRCC4 Rabbit Polyclonal Antibody (CAB1677)

SKU:
CAB1677
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-XRCC4 Antibody CAB1677
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-XRCC4 Antibody CAB1677
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-XRCC4 Antibody CAB1677
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-XRCC4 Antibody CAB1677
  • Epigenetics and Nuclear Signaling Antibodies 3 Anti-XRCC4 Antibody CAB1677
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:XRCC4 Rabbit Polyclonal Antibody
SKU:CAB1677
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human XRCC4 (NP_001304941.1?).
Sequence:MERK ISRI HLVS EPSI THFL QVSW EKTL ESGF VITL TDGH SAWT GTVS ESEI SQEA DDMA MEKG KYVG ELRK ALLS GAGP ADVY TFNF SKES CYFF FEKN LKDV SFRL GSFN LEKV ENPA EVIR ELIC YCLD TIAE NQAK NEHL QKEN ERLL RDWN DVQG RFEK CVSA KEAL ETDL YKRF ILVL NEKK TKIR SLHN KLLN AAQE REKD IKQE GETA ICSE MTAD RDPV YDES TDEE SENQ TDLS GLAS AAVS KDDS IISS LDVT DIAP SRKR RQRM QRNL GTEP KMAP QENQ LQEK ENSR PDSS LPET SKKE HISA ENMS LETL RNSS PEDL FDEI
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100
Synonyms:SSMED; hXRCC4; XRCC4
Positive Sample:Jurkat,THP-1,Rat testis
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:38kDa
Observed MW:55kDa

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site.

Purification Method:Affinity purification
Gene ID:7518
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using XRCC4 Rabbit pAb (CAB1677) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 1s.

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