XRCC3 Rabbit Polyclonal Antibody (CAB2134)
- SKU:
- CAB2134
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | XRCC3 Rabbit Polyclonal Antibody |
SKU: | CAB2134 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-346 of human XRCC3 (NP_001093588.1). |
Sequence: | ILTA LQLH QQKE RFPT QHQR LSLG CPVL DALL RGGL PLDG ITEL AGRS SAGK TQLA LQLC LAVQ FPRQ HGGL EAGA VYIC TEDA FPHK RLQQ LMAQ QPRL RTDV PGEL LQKL RFGS QIFI EHVA DVDT LLEC VNKK VPVL LSRG MARL VVID SVAA PFRC EFDS QASA PRAR HLQS LGAT LREL SSAF QSPV LCIN QVTE AMEE QGAA HGPL GFWD ERVS PALG ITWA NQLL VRLL ADRL REEE AALG CPAR TLRV LSAP HLPP SSCS YTIS AEGV RGTP GTQS H |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CMM6; XRCC3 |
Positive Sample: | HL-60 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Nucleus, perinuclear region. |
Calculated MW: | 38kDa |
Observed MW: | 37kDa |
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method: | Affinity purification |
Gene ID: | 7517 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |