The XRCC2 Polyclonal Antibody (CAB1800) is a crucial tool for researchers studying XRCC2, a protein involved in DNA repair processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the XRCC2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in the fields of genetics, cancer research, and molecular biology.XRCC2 is a key player in the homologous recombination DNA repair pathway, responsible for repairing double-strand breaks in DNA. Mutations in XRCC2 have been linked to increased susceptibility to certain types of cancer and genomic instability.
By understanding the function and regulation of XRCC2, researchers can gain valuable insights into the mechanisms of DNA repair and potentially develop targeted therapies for cancer treatment.The XRCC2 Polyclonal Antibody is a valuable tool for researchers looking to elucidate the role of XRCC2 in DNA repair pathways and its implications in cancer development. With its high specificity and reliability in Western blot applications, this antibody is essential for advancing our knowledge in genetics and oncology.
Product Name:
XRCC2 Polyclonal Antibody
SKU:
CAB1800
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human XRCC2 (NP_005422.1).
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents.
Purification Method:
Affinity purification
Gene ID:
7516
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using XRCC2 Rabbit pAb (CAB1800) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
