The XPNPEP3 Polyclonal Antibody (CAB14919) is a valuable tool for researchers studying XPNPEP3, a protein involved in various cellular processes including protein metabolism and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to XPNPEP3, this antibody enables accurate detection and analysis of the protein in a variety of cell types, making it well-suited for investigations in molecular biology and biochemistry.XPNPEP3, also known as aminopeptidase P3, plays a crucial role in protein degradation pathways and is implicated in processes such as cell cycle regulation and apoptosis.
Its involvement in these cellular functions underscores its relevance in disease research, particularly in cancer and metabolic disorders. By elucidating the functions of XPNPEP3, researchers can gain insights into potential therapeutic targets for these conditions and further expand our understanding of cellular mechanisms. The XPNPEP3 Polyclonal Antibody provides a reliable tool for exploring the roles of this protein and advancing scientific knowledge in this field.
Product Name:
XPNPEP3 Rabbit Polyclonal Antibody
SKU:
CAB14919
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human XPNPEP3 (NP_071381.1).
The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.
Purification Method:
Affinity purification
Gene ID:
63929
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using XPNPEP3 Rabbit pAb (CAB14919) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
