XKR8 Antibody (PACO47106)
- SKU:
- PACO47106
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | XKR8 Antibody (PACO47106) |
| Antibody SKU: | PACO47106 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human XK-related protein 8 protein (69-158AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: K562 whole cell lysate, 293T whole cell lysate. All lanes: XKR8 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa.. |
 | IHC image of PACO47106 diluted at 1:1000 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO47106 diluted at 1:1000 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis. |
| Synonyms: | XK-related protein 8 (hXkr8) [Cleaved into: XK-related protein 8, processed form], XKR8, XRG8 |
| UniProt Protein Function: | XKR8: Belongs to the XK family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 1p35.3Cellular Component: plasma membraneBiological Process: engulfment of apoptotic cell |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H6D3 |
| NCBI GenInfo Identifier: | 24431977 |
| NCBI Gene ID: | 55113 |
| NCBI Accession: | NP_060523.2 |
| UniProt Secondary Accession: | Q9H6D3 |
| UniProt Related Accession: | Q9H6D3 |
| Molecular Weight: | |
| NCBI Full Name: | XK-related protein 8 |
| NCBI Synonym Full Names: | XK related 8 |
| NCBI Official Symbol: | XKR8Â Â |
| NCBI Official Synonym Symbols: | XRG8; hXkr8Â Â |
| NCBI Protein Information: | XK-related protein 8 |
| UniProt Protein Name: | XK-related protein 8 |
| UniProt Synonym Protein Names: | |
| Protein Family: | XK-related protein |
| UniProt Gene Name: | XKR8Â Â |
| UniProt Entry Name: | XKR8_HUMAN |