The XK Polyclonal Antibody (CAB15109) is a key tool for researchers studying XK, a protein involved in the Kell blood group system and the maintenance of red blood cell membrane integrity. Raised in rabbits, this antibody is highly specific and reactive with human samples, providing reliable results in Western blot applications.XK is essential for the transport of various ions and molecules across the red blood cell membrane, making it crucial for normal blood cell function. Dysregulation of XK has been linked to various blood disorders, including Kell antigen deficiency and McLeod syndrome.
By targeting XK with this antibody, researchers can study its role in these conditions and explore potential therapeutic interventions.This antibody enables the detection and analysis of XK in a variety of cell types, making it an invaluable tool for studies in hematology and transfusion medicine. Understanding the function of XK is vital for advancing our knowledge of blood cell physiology and developing new treatments for blood-related diseases. Unlock the potential of XK research with the XK Polyclonal Antibody (CAB15109).
Product Name:
XK Rabbit Polyclonal Antibody
SKU:
CAB15109
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 59-138 of human XK (NP_066569.1).
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.
Purification Method:
Affinity purification
Gene ID:
7504
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using XK Rabbit pAb (CAB15109) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
