XG Antibody (PACO31096)
- SKU:
- PACO31096
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
XG Antibody (PACO31096)
The XG Polyclonal Antibody (PACO31096) is a valuable tool for researchers studying XG, a glycoprotein that plays a crucial role in immune regulation and cell adhesion. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding to the XG protein, this antibody enables the detection and analysis of XG in various cell types, making it essential for studies in immunology and cancer research.XG, also known as a key player in cell adhesion and immune response modulation, is involved in numerous biological processes, including inflammation and immune cell activation.
Its involvement in these pathways makes it a promising target for research aimed at understanding diseases like cancer, autoimmune disorders, and inflammatory conditions. By studying the function of XG, researchers can gain insights that may lead to the development of novel therapies targeting immune modulation and cell adhesion in various disease contexts.
| Antibody Name: | XG Antibody (PACO31096) |
| Antibody SKU: | PACO31096 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Glycoprotein Xg protein (22-143AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: XG antibody at 10µg/ml + Mouse heart tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 20, 22 kDa Observed band size: 20, 37, 60 kDa . |
| Background: | integral component of plasma membrane |
| Synonyms: | Glycoprotein Xg (Protein PBDX), XG, PBDX |
| UniProt Protein Function: | XG: the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X-specific end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed, but not expected to make a Y-chromosome specific gene product. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]Protein type: Membrane protein, integral; Cell surfaceChromosomal Location of Human Ortholog: Xp22.33Cellular Component: integral to plasma membraneDisease: Blood Group, Xg System |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X-specific end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed, but not expected to make a Y-chromosome specific gene product. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] |
| UniProt Code: | P55808 |
| NCBI GenInfo Identifier: | 213688346 |
| NCBI Gene ID: | 7499 |
| NCBI Accession: | NP_001135391.1 |
| UniProt Secondary Accession: | P55808,Q496N8, Q496N9, Q496P0, Q71BZ5, E9PCH1 |
| UniProt Related Accession: | P55808 |
| Molecular Weight: | 21,439 Da |
| NCBI Full Name: | glycoprotein Xg isoform 2 |
| NCBI Synonym Full Names: | Xg blood group |
| NCBI Official Symbol: | XGÂ Â |
| NCBI Official Synonym Symbols: | PBDXÂ Â |
| NCBI Protein Information: | glycoprotein Xg |
| UniProt Protein Name: | Glycoprotein Xg |
| UniProt Synonym Protein Names: | Protein PBDX |
| Protein Family: | Glycoprotein |
| UniProt Gene Name: | XGÂ Â |
| UniProt Entry Name: | XG_HUMAN |
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