The XAGE2 Polyclonal Antibody (PAC038726) offered by Assay Genie is specifically designed for research involving the XAGE2 protein, a tumor-associated antigen commonly found in various types of cancer. This antibody is produced in rabbits and is highly reactive with human samples, making it an ideal tool for studying XAGE2 expression in cancer cells.The XAGE2 protein is known to play a role in tumorigenesis and cancer progression, and its expression is often associated with poor prognosis in cancer patients. By using the XAGE2 Polyclonal Antibody, researchers can detect and analyze XAGE2 levels in a variety of cancer cell types, providing valuable insights into the role of this protein in cancer biology.
With its validated application in Western blotting, the XAGE2 Polyclonal Antibody is a reliable tool for researchers interested in investigating the molecular mechanisms underlying cancer development and progression. By elucidating the function of XAGE2 in cancer, this antibody has the potential to contribute to the development of targeted therapies and diagnostic tools for various types of cancer.
Antibody Name:
XAGE2 Antibody (PACO38726)
Antibody SKU:
PACO38726
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human X antigen family member 2 protein (1-111AA)
X antigen family member 2 (XAGE-2) (Cancer/testis antigen 12.2) (CT12.2) (G antigen family D member 3), XAGE2, GAGED3 XAGE2B
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq, Jul 2008]
