The X Antibody (PACO52230) is a highly specific and sensitive tool for researchers investigating the function and expression of the target antigen. This polyclonal antibody is recommended for use in various applications, including immunohistochemistry, flow cytometry, and ELISA. It has been validated for use with a wide range of samples and species, ensuring reliable and reproducible results.The X Antibody (PACO52230) targets a protein of interest involved in key cellular processes, making it an essential tool for studies in cell biology, molecular biology, and drug discovery.
Its versatility and high affinity for the target make it an ideal choice for researchers looking to explore the role of this protein in health and disease.By using the X Antibody (PACO52230) in your research, you can gain valuable insights into the function and regulation of the target protein, paving the way for new discoveries and potential therapeutic interventions. Don't miss out on the opportunity to enhance your research with this reliable and effective antibody.
Antibody Name:
X Antibody (PACO52230)
Antibody SKU:
PACO52230
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Hepatitis B virus genotype D subtype ayw
Immunogen:
Recombinant Hepatitis B virus genotype D subtype ayw Protein X protein (1-154AA)
Multifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 (By similarity).
Synonyms:
Protein X (HBx) (Peptide X) (pX), X
UniProt Protein Function:
Multifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 ().