The X Antibody (PACO51026) is a cutting-edge research tool designed for the study of CD300A, a key immune regulatory molecule. This polyclonal antibody, produced specifically for use in human samples, is highly reactive and validated for Western blot applications. By targeting the CD300A protein, researchers can effectively detect and analyze this important molecule in various cell types, making it a valuable tool for studies in immunology and cancer research.CD300A, also referred to as an immune inhibitory receptor, plays a pivotal role in modulating immune responses by regulating inflammation and inhibiting allergic reactions.
Its involvement in immune homeostasis makes it a promising target for research on cancer, autoimmune diseases, and chronic inflammatory conditions. Understanding the function of CD300A is essential for the development of therapies that manipulate immune responses in these disease contexts. Get your hands on the X Antibody (PACO51026) today and advance your research in the field of immunology and cancer biology.
Antibody Name:
X Antibody (PACO51026)
Antibody SKU:
PACO51026
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Hepatitis B virus genotype D subtype ayw
Immunogen:
Recombinant Hepatitis B virus genotype D subtype ayw Protein X protein (1-154AA)
Multifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 (By similarity).
Synonyms:
Protein X (HBx) (Peptide X) (pX), X
UniProt Protein Function:
Multifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 ().