WWP2 Rabbit Polyclonal Antibody (CAB2425)
- SKU:
- CAB2425
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | WWP2 Rabbit Polyclonal Antibody |
SKU: | CAB2425 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 151-400 of human WWP2 (NP_001257383.1). |
Sequence: | VPNG SALT DGSQ LPSR DSSG TAVA PENR HQPP STNC FGGR SRTH RHSG ASAR TTPA TGEQ SPGA RSRH RQPV KNSG HSGL ANGT VNDE PTTA TDPE EPSV VGVT SPPA APLS VTPN PNTT SLPA PATP AEGE EPST SGTQ QLPA AAQA PDAL PAGW EQRE LPNG RVYY VDHN TKTT TWER PLPP GWEK RTDP RGRF YYVD HNTR TTTW QRPT AEYV RNYE QWQS QRNQ LQGA MQHF SQRF LYQS SSAS TD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AIP2; WWp2-like; WWP2 |
Positive Sample: | A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 99kDa |
Observed MW: | 105kDa |
This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10.
Purification Method: | Affinity purification |
Gene ID: | 11060 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |