The WSB1 Polyclonal Antibody (CAB12195) is a valuable tool for researchers studying the WSB1 protein, which plays a key role in ubiquitination and protein degradation pathways. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to WSB1, researchers can accurately detect and analyze the protein in a variety of cell types, making it well-suited for studies in molecular biology and cellular processes.WSB1 is a substrate recognition component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, involved in targeting proteins for degradation via the proteasome.
Dysregulation of WSB1 has been implicated in various diseases, including cancer and neurodegenerative disorders, making it an attractive target for therapeutic interventions. Understanding the function and regulation of WSB1 is essential for developing novel treatments that target protein degradation pathways in disease states.
Product Name:
WSB1 Rabbit Polyclonal Antibody
SKU:
CAB12195
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 182-421 of human WSB1 (NP_056441.6).
This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
26118
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WSB1 Rabbit pAb (CAB12195) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 10s.
