WRB Rabbit Polyclonal Antibody (CAB7000)
- SKU:
- CAB7000
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | WRB Rabbit Polyclonal Antibody |
SKU: | CAB7000 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human WRB (NP_004618.2). |
Sequence: | SFSS FMSR VLQK DAEQ ESQM RAEI QDMK QELS TVNM MDEF ARYA RLER KINK MTDK LKTH VKAR TAQL AKI |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | WRB; CHD5 |
Positive Sample: | Mouse testis,Mouse skin,Rat lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 20kDa |
Observed MW: | 25kDa |
This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4.
Purification Method: | Affinity purification |
Gene ID: | 7485 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |