WFS1 Rabbit Polyclonal Antibody (CAB1705)
- SKU:
- CAB1705
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | WFS1 Rabbit Polyclonal Antibody |
SKU: | CAB1705 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human WFS1 (NP_005996.2). |
Sequence: | MDSN TAPL GPSC PQPP PAPQ PQAR SRLN ATAS LEQE RSER PRAP GPQA GPGP GVRD AAAP AEPQ AQHT RSRE RADG TGPT KGDM EIPF EEVL ERAK AGDP KAQT EVGK HYLQ LAGD TDEE LNSC TAVD WLVL AAKQ GRRE AVKL LRRC LADR RGIT SENE REVR QLSS ETDL ERAV RKAA LVMY WKLN PKKK KQVA VAEL LENV GQVN EHDG GAQP GPVP KSLQ KQRR MLER LVSS ESKN YIAL DDFV EITK KYAK GVIP SSLF LQDD EDDD ELAG KSPE DLPL R |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | WFS; WFRS; WFSL; CTRCT41; WFS1 |
Positive Sample: | HeLa,NIH/3T3,PC-12 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 100kDa |
Observed MW: | 100kDa |
This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7466 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |