The Wnt8 Antibody (PACO34514) is a crucial tool for researchers studying the Wnt signaling pathway, which plays a vital role in development, tissue homeostasis, and disease. This polyclonal antibody, generated in rabbits, is highly specific for detecting the Wnt8 protein in a variety of experimental settings, including Western blot analysis.Wnt8 is a member of the Wnt family of secreted glycoproteins that regulate cell proliferation, differentiation, and cell fate decisions during embryonic development and adult tissue maintenance.
Dysregulation of the Wnt signaling pathway has been implicated in various diseases, including cancer and neurodegenerative disorders.By using the Wnt8 Antibody, researchers can gain valuable insights into the function of the Wnt8 protein in different cell types and tissues. This antibody is an essential tool for investigations into the molecular mechanisms underlying Wnt signaling and its implications for human health and disease.
Antibody Name:
wnt8 Antibody (PACO34514)
Antibody SKU:
PACO34514
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Xenopus laevis
Immunogen:
Recombinant Xenopus laevis Protein Wnt-8 protein (23-358AA)
Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in ventral mesodermal patterning during embryogenesis. Mimics Nieuwkoop center activity. Causes dorsal mesodermal differentiation of animal cap ectoderm when coexpressed with noggin and nuclear, sequence-specific DNA-binding protein xBra. None of these molecules causes dorsal mesoderm formation when expressed alone.
Synonyms:
Protein Wnt-8 (XWnt-8), wnt8
UniProt Protein Function:
Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in ventral mesodermal patterning during embryogenesis. Mimics Nieuwkoop center activity. Causes dorsal mesodermal differentiation of animal cap ectoderm when coexpressed with noggin and nuclear, sequence-specific DNA-binding protein xBra. None of these molecules causes dorsal mesoderm formation when expressed alone.
