The WNT5A Rabbit Monoclonal Antibody (CAB19133) is a valuable tool for researchers studying the WNT5A protein, a member of the WNT family that plays a crucial role in cell signaling pathways. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.The WNT5A protein is involved in important cellular processes such as cell proliferation, differentiation, and migration. Dysregulation of WNT5A signaling has been linked to various diseases, including cancer, developmental disorders, and inflammatory conditions.
By using this antibody to detect and analyze WNT5A expression in different cell types, researchers can gain insights into the role of this protein in disease pathogenesis and potentially identify new therapeutic targets.Overall, the WNT5A Rabbit Monoclonal Antibody (CAB19133) is a valuable tool for scientists conducting research in the fields of cancer biology, developmental biology, and immunology. Its high specificity and sensitivity make it ideal for studying the intricate roles of WNT5A in various physiological and pathological conditions.
Product Name:
WNT5A Rabbit Monoclonal Antibody
SKU:
CAB19133
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 281-380 of human WNT5A (P41221).
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7474
Clone Number:
ARC0405
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using WNT5A Rabbit mAb (CAB19133) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
