WNT5A Rabbit Polyclonal Antibody (CAB12744)
- SKU:
- CAB12744
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | WNT5A Rabbit Polyclonal Antibody |
SKU: | CAB12744 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 116-217 of human WNT5A (NP_003383.4). |
Sequence: | STVD NTSV FGRV MQIG SRET AFTY AVSA AGVV NAMS RACR EGEL STCG CSRA ARPK DLPR DWLW GGCG DNID YGYR FAKE FVDA RERE RIHA KGSY ESAR |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IHC-P,1:100 - 1:500 |
Synonyms: | hWNT5A; WNT5A |
Positive Sample: | SKOV3,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 42kDa |
Observed MW: | 45kDa |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7474 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |