WNT2 Monoclonal Antibody
- SKU:
- CAB23997
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
WNT2 Monoclonal Antibody (CAB23997)
The WNT2 Monoclonal Antibody is a valuable tool for researchers studying the WNT2 protein, a critical signaling molecule involved in development, stem cell maintenance, and various diseases including cancer. This monoclonal antibody, produced in mice, shows high specificity and sensitivity in detecting WNT2 in human samples, making it ideal for experiments such as Western blotting and immunohistochemistry.WNT2 is a member of the WNT family of proteins, which play essential roles in cell proliferation, differentiation, and tissue patterning. Dysregulation of WNT signaling has been implicated in numerous diseases, making it an important target for therapeutic intervention.
The WNT2 Monoclonal Antibody enables researchers to study the expression and localization of WNT2 in different cell types and tissues, providing valuable insights into its functions and potential as a therapeutic target.By utilizing the WNT2 Monoclonal Antibody in their research, scientists can further our understanding of the intricate signaling pathways controlled by WNT proteins and their implications in health and disease. This antibody offers reliable and consistent results, empowering researchers to explore the role of WNT2 in various biological processes and disease states, ultimately paving the way for the development of novel treatments and interventions.
Product Name: | WNT2 Monoclonal Antibody |
Product Code: | CAB23997 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC58485 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:2000-1:8000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | NIH/3T3, Rat brain |
Cellular Location: | Secreted, extracellular matrix, extracellular space |
This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 231-330 of human WNT2 (NP_003382.1). |
Sequence: | GDYLW RKYNG AIQVV MNQDG TGFTV ANERF KKPTK NDLVY FENSP DYCIR DREAG SLGTA GRVCN LTSRG MDSCE VMCCG RGYDT SHVTR MTKCG CKFHW |
Synonyms: | IRP, INT1L1 |
Calculated MW: | 40kDa |
Observed MW: | 42kDa |