The WNT10B Polyclonal Antibody (CAB16717) is a valuable tool for researchers studying the WNT10B protein, a member of the Wnt signaling pathway that plays a key role in development and tissue homeostasis. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the WNT10B protein, this antibody allows for the detection and analysis of WNT10B expression in a variety of cell types.WNT10B is known to be involved in various cellular processes, including cell proliferation, differentiation, and migration, making it a crucial target for research in developmental biology, stem cell biology, and cancer biology.
Dysregulation of the WNT10B signaling pathway has been linked to a variety of diseases, including cancer, metabolic disorders, and developmental abnormalities. Thus, understanding the role of WNT10B in these contexts is essential for exploring its potential as a therapeutic target or biomarker.Overall, the WNT10B Polyclonal Antibody (CAB16717) offers researchers a valuable tool for studying the WNT10B protein and its implications in various biological processes and diseases. Its high reactivity and specificity make it a reliable choice for investigations in fields such as developmental biology, cancer research, and regenerative medicine.
Product Name:
WNT10B Rabbit Polyclonal Antibody
SKU:
CAB16717
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 260-340 of human WNT10B (NP_003385.2).
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
Purification Method:
Affinity purification
Gene ID:
7480
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using WNT10B Rabbit pAb (CAB16717) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
