The WNK1 Rabbit Monoclonal Antibody (CAB4223) is a high-quality research tool for studying WNK1, a protein kinase that plays a crucial role in regulating ion transport and maintaining cell volume. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.WNK1 is a key player in various physiological processes, including blood pressure regulation, cell proliferation, and ion transport. Dysregulation of WNK1 has been implicated in diseases such as hypertension, diabetes, and cancer, making it a promising target for drug development and treatment strategies.
By targeting the WNK1 protein, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and potentially identify new therapeutic approaches. The WNK1 Rabbit Monoclonal Antibody (CAB4223) provides a reliable tool for detecting and analyzing WNK1 expression in a variety of cell types, making it a valuable asset for studies in molecular biology, pharmacology, and disease pathology.
Product Name:
WNK1 Rabbit Monoclonal Antibody
SKU:
CAB4223
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WNK1 (Q9H4A3).
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.
Purification Method:
Affinity purification
Gene ID:
65125
Clone Number:
ARC0932
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse kidney, using WNK1 Rabbit mAb (CAB4223) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
