The WLS Polyclonal Antibody (CAB18328) is specifically designed for research involving the Wntless (WLS) protein, a key player in the Wnt signaling pathway crucial for embryonic development and cancer progression. This rabbit polyclonal antibody is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunofluorescence.The WLS protein is essential for the secretion and transport of Wnt ligands, which are crucial for regulating cell proliferation, differentiation, and migration. Dysregulation of the Wnt signaling pathway has been linked to various diseases, including cancer and developmental disorders.
The WLS Polyclonal Antibody enables accurate detection and analysis of the WLS protein in different cell types, making it an invaluable tool for studying Wnt signaling and its role in disease progression.Researchers in the fields of developmental biology, oncology, and stem cell research will find the WLS Polyclonal Antibody essential for investigating the mechanisms underlying Wnt signaling and its implications for disease. With its high specificity and sensitivity, this antibody provides a reliable tool for unraveling the complexities of the WLS protein and its functions in various biological processes.
Product Name:
WLS Rabbit Polyclonal Antibody
SKU:
CAB18328
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 43-232 of human WLS (NP_001002292.3).
Enables Wnt-protein binding activity and identical protein binding activity. Involved in positive regulation of cell communication and protein transport. Located in several cellular components, including Golgi apparatus; early endosome; and endoplasmic reticulum membrane.
Purification Method:
Affinity purification
Gene ID:
79971
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WLS Rabbit pAb (CAB18328) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
