The WIPI1 Rabbit Monoclonal Antibody (CAB9600) is a powerful tool for researchers studying WIPI1, a key protein involved in autophagy and intracellular trafficking processes. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for WIPI1 in a variety of experimental settings.WIPI1 is known to play a crucial role in the formation of pre-autophagosomal structures, leading to the initiation of autophagy, a cellular process crucial for maintaining cellular homeostasis and responding to stress conditions. Dysregulation of WIPI1 has been implicated in various diseases, including neurodegenerative disorders and cancer.
With its ability to specifically target WIPI1, this antibody is an essential tool for researchers looking to better understand the complex mechanisms underlying autophagy and its role in disease pathology. Validated for use in techniques such as immunofluorescence and immunohistochemistry, the WIPI1 Rabbit Monoclonal Antibody (CAB9600) offers a reliable and accurate way to study WIPI1 expression and localization in various cell types and tissues. Uncover the mysteries of autophagy with this cutting-edge antibody and advance your research in the fields of cell biology and disease mechanisms.
Product Name:
WIPI1 Rabbit Monoclonal Antibody
SKU:
CAB9600
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WIPI1 (Q5MNZ9).
This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55062
Clone Number:
ARC1652
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using WIPI1 Rabbit mAb (CAB9600) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
