The WIPF2 Monoclonal Antibody (PACO13242) is a powerful tool for researchers studying WIPF2, a protein involved in cell migration and actin dynamics. This antibody, produced in mice, exhibits high specificity and sensitivity for detecting WIPF2 in human samples, making it ideal for use in Western blot and immunofluorescence applications.WIPF2, also known as WAVE2, plays a key role in regulating the cytoskeleton and promoting cell movement. Its function in cell migration makes it a crucial player in processes such as wound healing, immune cell trafficking, and cancer metastasis.
By targeting WIPF2, researchers can gain insights into these biological processes and potentially develop targeted therapies for conditions where cell migration is dysregulated.With its ability to specifically detect WIPF2, the PACO13242 antibody is a valuable tool for scientists conducting research in cell biology, cancer biology, and immunology. Its reliability and versatility make it a standout choice for studying WIPF2 and its implications in various disease contexts.
WAS/WASL interacting protein family, member 2;WIPF2;WICH;WIRE ;
UniProt Protein Function:
WIRE: Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system. Belongs to the verprolin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 17q21.2Cellular Component: actin filament; cytosolMolecular Function: actin filament binding; protein bindingBiological Process: actin cortical patch assembly; actin cortical patch localization; actin filament-based movement; endocytosis; positive regulation of actin nucleation; regulation of cell shape
UniProt Protein Details:
NCBI Summary:
This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery. [provided by RefSeq, Jul 2008]
