The WIPF1 Polyclonal Antibody (CAB17003) is a valuable tool for researchers studying WIPF1, a protein involved in cell migration and actin cytoskeletal dynamics. Raised in rabbits, this antibody is highly specific and sensitive to human samples, making it ideal for Western blot applications. By binding to the WIPF1 protein, this antibody allows for the detection and analysis of WIPF1 in various cell types, essential for studies in cell biology, cancer research, and immunology.
WIPF1, also known as WAVE1, is a key regulator of actin dynamics essential for cell movement and shape changes. Its role in cell migration and adhesion makes it a significant target for research into cancer metastasis, immune cell function, and neuronal development. Understanding the function of WIPF1 is crucial for elucidating its role in these processes and developing targeted therapies for related diseases and disorders.
Product Name:
WIPF1 Rabbit Polyclonal Antibody
SKU:
CAB17003
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human WIPF1 (NP_001070737.1).
This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
7456
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WIPF1 Rabbit pAb (CAB17003) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
