WIF1 Rabbit Polyclonal Antibody (CAB12969)
- SKU:
- CAB12969
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | WIF1 Rabbit Polyclonal Antibody |
SKU: | CAB12969 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-220 of human WIF1 (NP_009122.2). |
Sequence: | GPPQ EESL YLWI DAHQ ARVL IGFE EDIL IVSE GKMA PFTH DFRK AQQR MPAI PVNI HSMN FTWQ AAGQ AEYF YEFL SLRS LDKG IMAD PTVN VPLL GTVP HKAS VVQV GFPC LGKQ DGVA AFEV DVIV MNSE GNTI LQTP QNAI FFKT CQQA ECPG GCRN GGFC NERR ICEC PDGF HGPH CEKA LCTP RCMN |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | WIF-1; WIF1 |
Positive Sample: | 293T transfected with WIF1 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
Purification Method: | Affinity purification |
Gene ID: | 11197 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |