Based on the product information in the provided URL, here is a potential product description:The WHSC1L1 Polyclonal Antibody (CAB5577) is a vital tool for researchers studying WHSC1L1, a protein involved in epigenetic regulation and implicated in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications. By targeting the WHSC1L1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable asset for studies in cancer research and epigenetics.WHSC1L1, also known as MMSET (Multiple Myeloma SET domain), is a key player in chromatin remodeling and gene regulation, with implications in oncogenesis and tumor progression.
Its involvement in epigenetic mechanisms underscores its significance as a potential therapeutic target for cancer and other diseases. By elucidating the functions of WHSC1L1, researchers can uncover valuable insights into disease mechanisms and potentially identify novel treatment strategies.Overall, the WHSC1L1 Polyclonal Antibody (CAB5577) offers researchers a reliable and specific tool for investigating the role of WHSC1L1 in cellular processes and disease pathogenesis, ultimately advancing our understanding of epigenetics and providing potential avenues for therapeutic development.
Product Name:
NSD3/WHSC1L1 Rabbit Polyclonal Antibody
SKU:
CAB5577
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-600 of human NSD3/NSD3/WHSC1L1 (NP_060248.2).
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described.
Purification Method:
Affinity purification
Gene ID:
54904
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NSD3/NSD3/WHSC1L1 antibody (CAB5577) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
