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NSD3/WHSC1L1 Rabbit Polyclonal Antibody (CAB2317)

SKU:
CAB2317
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NSD3/WHSC1L1 Rabbit Polyclonal Antibody
SKU:CAB2317
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 430-590 of human NSD3/WHSC1L1 (NP_075447.1).
Sequence:PEQT NAGE VASS LSST EIRR HSQR RHTS AEEE EPPP VKIA WKTA AARK SLPA SITM HKGS LDLQ KCNM SPVV KIEQ VFAL QNAT GDGK FIDQ FVYS TKGI GNKT EISV RGQD RLII STPN QRNE KPTQ SVSS PEAT SGST GSVE KKQQ RRSI RTRS ESEK S
Tested Applications:WB ELISA
Recommended Dilution:WB,1:200 - 1:2000
Synonyms:KMT3F; KMT3G; WHISTLE; WHSC1L1; pp14328; NSD3/WHSC1L1
Positive Sample:293,HeLa
Conjugate:Unconjugated
Cellular Localization:Chromosome, Nucleus.
Calculated MW:162kDa
Observed MW:85kDa

This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described.

Purification Method:Affinity purification
Gene ID:54904
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using NSD3/WHSC1L1 Rabbit pAb (CAB2317).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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