The WFikkn1 Polyclonal Antibody (PAC063183) is a valuable tool for researchers studying the WFikkn1 protein, which is involved in various cellular processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the WFikkn1 protein, this antibody allows for efficient detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and cell signaling.The WFikkn1 protein is known for its involvement in regulating cell growth, differentiation, and survival, making it a key player in various physiological and pathological processes.
Its role in cell signaling pathways and gene expression modulation makes it a promising target for research into diseases such as cancer, developmental disorders, and neurodegenerative conditions. Understanding the function of WFikkn1 is essential for unlocking its therapeutic potential and developing novel treatment strategies for these conditions.
Antibody Name:
WFIKKN1 Antibody (PACO63183)
Antibody SKU:
PACO63183
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 protein (187-207AA)
IHC image of PACO63183 diluted at 1:300 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity (By similarity).
Synonyms:
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 (Growth and differentiation factor-associated serum protein 2) (GASP-2) (hGASP-2) (WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing protein), WFIKKN1, C16orf12 GASP2 WFIKKN
UniProt Protein Function:
WFIKKN1: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Belongs to the WFIKKN family.Protein type: Inhibitor; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 16p13.3Cellular Component: extracellular regionMolecular Function: metalloendopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; protein bindingBiological Process: palate development; negative regulation of protein binding; muscle fiber development; skeletal development; negative regulation of DNA binding
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1
UniProt Synonym Protein Names:
Growth and differentiation factor-associated serum protein 2; GASP-2; hGASP-2; WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing protein
Protein Family:
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein
