| UniProt Protein Function: | WFDC8: Protein type: Secreted; Membrane protein, integral; Secreted, signal peptideChromosomal Location of Human Ortholog: 20q13.12Cellular Component: extracellular regionMolecular Function: serine-type endopeptidase inhibitor activity |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8IUA0 |
| NCBI GenInfo Identifier: | 153946387 |
| NCBI Gene ID: | 90199 |
| NCBI Accession: | NP_570966.2 |
| UniProt Secondary Accession: | Q8IUA0,Q5TDV2, Q96A34, E1P623 |
| UniProt Related Accession: | Q8IUA0 |
| Molecular Weight: | 27,824 Da |
| NCBI Full Name: | WAP four-disulfide core domain protein 8 |
| NCBI Synonym Full Names: | WAP four-disulfide core domain 8 |
| NCBI Official Symbol: | WFDC8Â Â |
| NCBI Official Synonym Symbols: | WAP8; C20orf170; dJ461P17.1Â Â |
| NCBI Protein Information: | WAP four-disulfide core domain protein 8 |
| UniProt Protein Name: | WAP four-disulfide core domain protein 8 |
| UniProt Synonym Protein Names: | Putative protease inhibitor WAP8 |
| Protein Family: | WAP four-disulfide core domain protein |
| UniProt Gene Name: | WFDC8Â Â |
| UniProt Entry Name: | WFDC8_HUMAN |
