The WFDC8 Antibody (PAC04798) is a highly specific and sensitive tool for researchers studying the WFDC8 protein, a member of the whey acidic protein family. This polyclonal antibody, produced in rabbits, has been validated for use in various applications such as immunohistochemistry and ELISA, providing reliable detection and quantification of WFDC8 in biological samples.WFDC8 is known to play a role in the regulation of protease activity and has been implicated in various physiological processes, including inflammation, tissue remodeling, and cancer progression.
By targeting WFDC8 with this antibody, researchers can gain insight into its functional roles in these pathways, leading to a better understanding of its potential as a therapeutic target.With its high specificity and sensitivity, the WFDC8 Antibody (PAC04798) is a valuable tool for investigating the biological functions of WFDC8 in health and disease. Its application in research areas such as oncology, immunology, and biomarker discovery make it an essential component of any study aiming to elucidate the role of WFDC8 in biological processes.
WFDC8: Protein type: Secreted; Membrane protein, integral; Secreted, signal peptideChromosomal Location of Human Ortholog: 20q13.12Cellular Component: extracellular regionMolecular Function: serine-type endopeptidase inhibitor activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008]
