The WFDC1 Rabbit Polyclonal Antibody (CAB17193) is a valuable tool for researchers studying WFDC1, a protein involved in various biological processes including immune regulation and cancer progression. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blotting applications. By specifically binding to the WFDC1 protein, this antibody enables the accurate detection and analysis of WFDC1 in different cell types, making it an ideal choice for immunology and cancer research studies.
WFDC1, also known as WAP four-disulfide core domain protein 1, is known to play a role in immune function and has been implicated in cancer development and progression. Its involvement in these critical biological processes makes it a key target for investigations into diseases such as cancer and autoimmune disorders. Understanding the function and regulation of WFDC1 is essential for developing new therapeutic approaches that target this protein and its associated pathways.
Product Name:
WFDC1 Rabbit Polyclonal Antibody
SKU:
CAB17193
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 111-220 of human WFDC1 (NP_067020.2).
This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
58189
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WFDC1 Rabbit pAb (CAB17193) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
