The Wee1 Monoclonal Antibody offered by Assay Genie is a valuable tool for research involving the protein Wee1, a critical regulator of cell cycle progression. This monoclonal antibody, produced in mice, is highly specific for human samples and has been validated for use in a variety of applications, including Western blotting.Wee1 is a key protein involved in regulating the cell cycle by inhibiting the activity of cyclin-dependent kinases. Dysregulation of Wee1 has been linked to various diseases, including cancer, making it an important target for research in oncology. By utilizing the Wee1 Monoclonal Antibody, researchers can detect and analyze the expression of Wee1 in different cell types, providing valuable insights into its role in cell cycle control and potential therapeutic targeting.
Overall, the Wee1 Monoclonal Antibody from Assay Genie is a reliable tool for studying the function of the Wee1 protein in various biological processes, particularly in the context of cancer research. Its specificity and sensitivity make it a valuable asset for scientists looking to further understand the mechanisms underlying cell cycle regulation and potential therapeutic interventions.
Product Name:
WEE1 Monoclonal Antibody
SKU:
CAB22275
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WEE1 (NP_003381.1).
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
Purification Method:
Affinity purification
Gene ID:
7465
Clone Number:
ARC57004
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded mouse lung using WEE1 Rabbit mAb (CAB22275) at dilution of 1:100(40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
