The WDR77 Polyclonal Antibody (CAB7134) is a vital tool for scientists studying the function of WDR77, a protein involved in various cellular processes and critical for gene regulation. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By targeting the WDR77 protein, researchers can accurately detect and analyze its expression in different cell types, making it an invaluable resource for studies in molecular biology and cancer research.
WDR77, also known as androgen receptor coactivator p44, is known to play a pivotal role in gene transcription and epigenetic regulation. Its involvement in these processes makes it a promising target for investigations into cancer development, making this antibody an essential tool for researchers studying cancer biology. By gaining a better understanding of WDR77's function, scientists can uncover new avenues for developing targeted cancer therapies and potentially revolutionize treatment strategies for cancer patients.
Product Name:
WDR77 Rabbit Polyclonal Antibody
SKU:
CAB7134
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 153-243 of human WDR77 (NP_077007.1).
The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
79084
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using WDR77 antibody (CAB7134) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
