The WDR66 Polyclonal Antibody (PACO39474) is a valuable tool for researchers studying WDR66, a protein involved in DNA repair and cell cycle regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the WDR66 protein, this antibody allows for the detection and analysis of WDR66 in a variety of cell types, making it an ideal choice for studies in genetics and cancer research.WDR66 is known for its role in maintaining genomic stability and promoting cell survival under stressful conditions. Its involvement in repairing DNA damage and controlling cell division highlights its importance in cancer development and therapy.
By investigating the function of WDR66, researchers can gain insights into the mechanisms of tumorigenesis and potentially identify new targets for cancer treatment.Overall, the WDR66 Polyclonal Antibody (PACO39474) provides researchers with a reliable tool for studying the biological functions of WDR66 and its implications in cancer biology. Its specificity and sensitivity make it a valuable asset for advancing our understanding of DNA repair mechanisms and their relevance to human health.
Antibody Name:
WDR66 Antibody (PACO39474)
Antibody SKU:
PACO39474
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human WD repeat-containing protein 66 protein (1-1154AA)
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO39474 at dilution of 1:100.
Synonyms:
Cilia- and flagella-associated protein 251 (CFAP251) (WD repeat-containing protein 66), WDR66, CFAP251
UniProt Protein Function:
WDR66: This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]Chromosomal Location of Human Ortholog: 12q24.31
UniProt Protein Details:
NCBI Summary:
This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]
