The WDR6 Polyclonal Antibody (CAB7780) is a valuable tool for researchers investigating the protein WDR6, which plays a key role in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the WDR6 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in cell biology, genetics, and cancer research.
WDR6, a member of the WD repeat protein family, is involved in diverse biological functions such as cell cycle regulation, signal transduction, and DNA repair. Its versatility and importance in cellular pathways make it a promising target for further investigation in the fields of molecular biology and biomedicine. By understanding the functions and mechanisms of WDR6, researchers can uncover new insights into disease processes and potentially develop innovative therapeutic approaches.
Product Name:
WDR6 Rabbit Polyclonal Antibody
SKU:
CAB7780
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human WDR6 (NP_060501.3).
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
11180
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using WDR6 Rabbit pAb (CAB7780) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
