The WDR5 Rabbit Monoclonal Antibody (CAB3259) is a valuable tool for researchers studying the protein WDR5, a key player in epigenetic regulation and gene expression. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications.WDR5 is a crucial component of the MLL complex, which plays a vital role in the maintenance of gene expression patterns and stem cell renewal. Dysregulation of WDR5 has been implicated in various diseases, including cancer and neurological disorders. By targeting WDR5 with this monoclonal antibody, researchers can better understand the mechanisms underlying these diseases and explore potential therapeutic interventions.
The high specificity and sensitivity of the WDR5 Rabbit Monoclonal Antibody make it an essential tool for studies in epigenetics, developmental biology, and cancer research. Its ability to detect WDR5 in various cell types and tissues makes it a versatile option for researchers seeking to unravel the complex regulatory networks that govern gene expression. Unlock the potential of your research with the WDR5 Rabbit Monoclonal Antibody (CAB3259).
Product Name:
WDR5 Rabbit Monoclonal Antibody
SKU:
CAB3259
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 235-334 of human WDR5 (NP_060058.1).
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
11091
Clone Number:
ARC0769
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using WDR5 Rabbit mAb (CAB3259) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
