The WDR5 Polyclonal Antibody (CAB13582) is a valuable tool for research involving the WDR5 protein, known for its essential role in epigenetic regulation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the WDR5 protein, researchers can accurately detect and analyze WDR5 expression in various cell types, making it a versatile tool for studies in epigenetics and gene regulation.WDR5 is a key component of the SET1/MLL histone methyltransferase complex, crucial for the maintenance of proper gene expression and cellular function.
Dysregulation of WDR5 has been implicated in various diseases, including cancer and developmental disorders. By studying the function and regulation of WDR5, researchers can gain insights into the mechanisms underlying these conditions and potentially identify targets for therapeutic intervention.Overall, the WDR5 Polyclonal Antibody (CAB13582) is a valuable resource for researchers investigating the intricate mechanisms of epigenetic regulation and gene expression, with potential implications for understanding and treating a variety of diseases.
Product Name:
WDR5 Rabbit Polyclonal Antibody
SKU:
CAB13582
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human WDR5 (NP_438172.1).
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
11091
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using WDR5 antibody (CAB13582) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
