The WDR4 Polyclonal Antibody (CAB16487) is a valuable tool for researchers studying the WDR4 protein, which is involved in various cellular processes such as ribosome biogenesis and mRNA processing. This antibody, developed using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the WDR4 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it ideal for investigations in molecular biology and cancer research.WDR4, also known as WD repeat domain 4, plays a crucial role in maintaining cellular homeostasis by regulating essential biological pathways.
Its involvement in ribosome assembly and RNA processing highlights its importance in cellular function and potential implications in disease development. By elucidating the functions of WDR4, researchers can gain valuable insights into its potential as a therapeutic target in diseases such as cancer and genetic disorders.Overall, the WDR4 Polyclonal Antibody (CAB16487) provides a reliable tool for researchers looking to explore the functions and mechanisms of the WDR4 protein in various biological processes. Its specificity, sensitivity, and versatility make it a valuable asset in advancing our understanding of cellular biology and disease pathology.
Product Name:
WDR4 Rabbit Polyclonal Antibody
SKU:
CAB16487
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-250 of human WDR4 (NP_061139.2).
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10785
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WDR4 Rabbit pAb (CAB16487) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
