The WDR37 Monoclonal Antibody (PAC042850) is a valuable tool for researchers studying the function of WDR37, a key protein involved in cellular processes such as DNA replication and repair. This antibody, produced in vitro using hybridoma technology, specifically targets WDR37 in human samples and is validated for use in immunofluorescence and immunohistochemistry applications. By binding to WDR37, this antibody allows for the visualization and analysis of WDR37 expression in various cell types, making it a versatile tool for studies in molecular biology and cancer research.WDR37, also known as WD repeat-containing protein 37, plays a crucial role in maintaining genomic stability and regulating cell cycle progression.
Its involvement in DNA repair mechanisms and chromosome segregation highlights its importance in preventing mutations and genomic instability. Research into the function of WDR37 is essential for understanding the mechanisms underlying cancer development and progression, as well as identifying potential targets for novel cancer therapies.Overall, the WDR37 Monoclonal Antibody (PAC042850) offers researchers a reliable tool for investigating the role of WDR37 in cellular processes and disease pathogenesis.
Western blot. All lanes: WDR37 antibody at 7µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 55, 30 kDa. Observed band size: 55 kDa.
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO42850 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO42850 at dilution of 1:100.
Synonyms:
WD repeat-containing protein 37, WDR37, KIAA0982
UniProt Protein Function:
WDR37: 3 isoforms of the human protein are produced by alternative splicingProtein type: Unknown functionChromosomal Location of Human Ortholog: 10p15.3
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
