WDR35 Rabbit Polyclonal Antibody (CAB12824)
- SKU:
- CAB12824
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | WDR35 Rabbit Polyclonal Antibody |
SKU: | CAB12824 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 871-1170 of human WDR35 (NP_065830.2). |
Sequence: | CSQP KAAV DTCV HLNQ WNKA VELA KNHS MKEI GSLL ARYA SHLL EKNK TLDA IELY RKAN YFFD AAKL MFKI ADEE AKKG SKPL RVKK LYVL SALL IEQY HEQM KNAQ RGKV KGKS SEAT SALA GLLE EEVL STTD RFTD NAWR GAEA YHFF ILAQ RQLY EGCV DTAL KTAL HLKD YEDI IPPV EIYS LLAL CACA SRAF GTCS KAFI KLKS LETL SSEQ KQQY EDLA LEIF TKHT SKDN RKPE LDSL MEGG EGKL PTCV ATGS PITE YQFW MCSV CKHG VLAQ EISH YSFC PLCH SPVG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CED2; IFTA1; SRTD7; FAP118; IFT121; CFAP118; WDR35 |
Positive Sample: | LO2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cilium axoneme, cilium basal body, cytoskeleton, microtubule organizing center. |
Calculated MW: | 134kDa |
Observed MW: | 133kDa |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.
Purification Method: | Affinity purification |
Gene ID: | 57539 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |